Improved in Vitro Blood Compatibility of Polycaprolactone Nanowire Surfaces

Improved in Vitro Blood Compatibility of Polycaprolactone Nanowire Surfaces

There are a multitude of polymeric materials currently utilized to prepare a variety of blood-contacting implantable medical devices. These devices include tissue grafts, coronary artery and vascular stents, and orthopedic implants. The thrombogenic nature of such materials can cause serious complications in patients, and ultimately lead to functional failure. To date, there is no truly hemocom...

Smooth Muscle Cell Functionality on Collagen Immobilized Polycaprolactone Nanowire Surfaces

Inhibition of smooth muscle cell (SMC) proliferation and preservation of a differentiated state are important aspects in the management, avoidance and progression of vascular diseases. An understanding of the interaction between SMCs and the biomaterial involved is essential for a successful implant. In this study, we have developed collagen immobilized nanostructured surfaces with controlled a...

Effects of polycaprolactone nanowire surfaces on adipogenic and chondrogenic differentiation of adipose-derived stem cells

106 ©2014 Society for Biomaterials

Amelioration of Blood Compatibility and Endothelialization of Polycaprolactone Substrates by Surface-Initiated Atom Transfer Radical Polymerization

Towards an Improved Compatibility